БИОЛОГИЧЕСКАЯ АКТИВНОСТЬ ПРОТИВ РАКОВЫХ КЛЕТОК ЭКСТРАКТОВ ЭНДОФИТНЫХ ГРИБКОВ, ВЫДЕЛЕННЫХ ИЗ РАСТЕНИЯ CYNARA SCOLYMUS L.
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Аннотация
На сегодняшний день количество опубликованных работ по фитохимическим и биологическим исследованиям вторичных метаболитов, продуцируемых эндофитными грибами, увеличилось в различных научных журналах и научной литературе по всему миру. В результате этих исследований были созданы новые антибактериальные, антиоксидантные и противовоспалительные препараты, а также новые типы биопрепаратов, которые помогают бороться с различнқми сельскохозяйственными вредителями. Например, на основе вторичных метаболитов, выделенных из эндофитных грибов, созданы такие препараты, как пенициллин, aспергиллин, фумигацин, клавацин, септептомицин, Биомицин, ауреомицин, хлормицетин, террамицин, эритромицин, группа неомицина (колимицин, мицерин, мономицин). В этой исследовательской работе проанализирована биологическая активность эндофитных грибков, полученных на основе растения Cynara scolymus L., против раковых клеток. Результаты показали, что экстракты двух эндофитных грибков, проявляют эффективное действие против HeLa, раковых клеток карциномы гортани Hep-2 (ATCC: CCL-23) и рака молочной железы HBL-100.
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