sg
O‘zbekcha

SYNTHESIS AND STUDY OF COMPLEX COMPOUNDS OF 3-AMINO 1,2,4-TRIAZOLE WITH SALTS OF Co (II), Ni (II) AND Cu (II)

Authors

  • National University of Uzbekistan
  • National University of Uzbekistan
  • National University of Uzbekistan
  • National University of Uzbekistan

Keywords:

Amitrol, nickel sulfate, infrared spectroscopy, complex, solubility, ligand, thermal analysis.

Abstract

Methods for the synthesis of complex compounds of 3-amino-1,2,4-triazole with Co (II), Ni (II) and Cu (II) salts have been developed, and the composition and structure of the synthesized complex compounds have been studied using modern physicochemical research methods. It was established that in complex formation reactions the 3-amino-1,2,4-triazole ligand is coordinated through the fourth nitrogen atom of the triazole ring.

Author Biographies

  • , National University of Uzbekistan

    O‘zbebkiston milliy universiteti, Kimyo fakulteti Noorganik kimyo kafedrasi PhD doktoranti

  • , National University of Uzbekistan

    O‘zbebkiston milliy universiteti, Kimyo fakulteti Noorganik kimyo kafedrasi dotsenti, PhD

  • , National University of Uzbekistan

    O‘zbebkiston milliy universiteti, Kimyo fakulteti Noorganik kimyo kafedrasi dotsenti, PhD

  • , National University of Uzbekistan

    O‘zbebkiston milliy universiteti, Kimyo fakulteti Noorganik kimyo kafedrasi professori

References

Romain Noel, Xinyi Song, Rong Jiang, Michael J. Chalmers, Patrick R. Griffin, and Theodore M. Kamenecka. Efficient Methodology for the Synthesis of 3-amino-1,2,4–triazoles. // J.Org.Chem. 2009,74,19,7595-7597.

Иванова Ю.С., Цаплин Г.В., Попков С.В. Метод получения N1-замещенных – 4–(1,2,4–триазол–1–илметил)–1,2,3–триазолов и изучение их фунгицидной активности. // Успехи в химии и химической технологии. Том ХХХIV.2020. №8.

Khadir A., Verreault J., Averill DA., Inhibition of antioxidants and hyperthermia enhance bleomycin – induced cytotoxicity and lipid peroxidation in Chinese hamster ovary cells. // Arch Biochem Biophys., 1999 Oct; 370(2):163-75.

MacCabe AP, Miro P, Ventura L, Ramon D. Glucose uptake in germinating Aspergillus nidulans conidia: involvement of the creA and sorA genes. // Microbiology 149:2129-2136.

Fauchere JL, Boutin JA. Исследования субстратной специфичности и ингибирования серотонин-N-ацетилтрансферазы человека. // J. Biol. Chem. 2000. 275 (12): 8794–805.

Lowe RF, Nelson J, Dang TN, Crowe PD, Paxuja A, McCarthy JR, Grigoriadis DE, Conlon P, Saunders J, Chen C, Szabo T, Chen TK, Bozigian. Rational design, synthesis, and structure−activity relationships of aryltriazoles as novel corticotropin-releasing factor-1 receptor antagonists. // HJ Med. Kimyo 2005; 48: 1540–1549. [PubMed: 15743196].

Marino JP, Fisher PW, Hofmann GA, Kirkpatrick RB, Janson CA, Jonson RK, Ma C, Mattern M, Meek TD, Rayan MD, Schulz C, Smit WW, Tew DG, Tomazek TA, Veber DF, Xiong WC, Yamamoto Y , Yamashita K, Yang G, Tompson SK. Highly potent inhibitors of methionine aminopeptidase-2 based on a 1,2,4- triazole pharmacophore. // J. Med. Kimyo 2007;50:3777–3785. [PubMed: 17636946].

А. В. Васильев, Е. В. Гриненко, А. О. Щукин, Т. Г. Федулина Инфракрасная спектроскопия органических и природных соединений. САНКТ-ПЕТЕРБУРГ СПбГЛТА 2007. Ст-16.

Шаталова Т.Б., Шляхтин О.А., Веряева Е. Методы термического анализа. - Москва: 2011

Downloads

Published

2023-11-16

Most read articles by the same author(s)

1 2 3 4 > >>