DETERMINATION OF THE CONTENT OF FLAVONOIDS IN HAWTHORN
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Abstract
Determination of flavonoids in yellow hawthorn, common in Uzbekistan. Flavonoids in the sample were determined using liquid chromatography. Dihydroquercetin, quercetin and rutin were found in freshly cut yellow hawthorn. It was found that the amount of flavonoids in dried hawthorn has decreased
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References
N Liu, Y. Liu, LL Hu, YL Suo, L. Zhang, F. Jin, XA Feng, N. Teng, Y. Li. Effects of dietary supplementation of quercetin on performance, egg quality, cecal microflora populations, and antioxidant status in laying hens. Poultry Science . Volume 93, Issue 2 , 1 February 2014, Pages 347-353. https://doi.org/10.3382/ps.2013-03225.
Aditya Ganeshpurkar , Ajay K Saluja.The Pharmacological Potential of Rutin. Saudi pharmaceutical journal. 2017 Feb;25(2):149-164. doi : 10.1016/j.jsps.2016.04.025.
Yu Duan 1 , No Sun 1 , Min Xue 1 , Xiaolan Wang 1 , Hu Yang 2 Synthesis of regioselectively acylated quercetin analogues with improved antiplatelet activity. Mol Med Rep. 2017 Dec;16(6):9735-9740. doi:10.3892/mmr.2017.7781.
Maria Choleva, Vassiliki Boulougouri, Anthy Panara, Eirini Panagopoulou, Antonia Chiou, Nikolaos S. Thomaidis, Smaragdi Antonopouloua, Elizabeth Fragopoulou. Evaluation of anti-platelet activity of grape pomace extracts. Food & Function., 2019, 10, P. 8069-8080. DOI : https://doi.org/10.1039/C9FO02138H
Solomon Habtemariam. Rutin as a Natural Therapy for Alzheimer's Disease: Insights into its Mechanisms of Action. Current medicinal chemistry. 2016;23(9):860-73. doi : 10.2174/0929867323666160217124333.
Amélia Miranda Gómez Rodrigues 1 , Fralini Dos Santos Marcilio , Michelle Frazão Muzitano , Arthur Giraldi-Guimarães. Therapeutic potential of treatment with the flavonoid rutin after cortical focal ischemia in rats. Brain Research . Volume 1503 , 29 March 2013, Pages 53-61
doi : 10.1016/j.brainres.2013.01.039.
Cong Sui , Yichao Wu , Ran Zhang , Tiantian Zhang , Yang Zhang , Jiaojiao Xi , Yanyu Ding , Jiyue Wen , Yong Hu . Rutin Inhibits the Progression of Osteoarthritis Through CBS - Mediated RhoA/ROCK Signaling . DNA and Cell Biology Vol. 41, No. 6 .2022.P.617-630.Doi: https://doi.org/10.1089/dna.2021.1182
Fan Wan , Hui Han , Ruqing Zhong , Mengyu Wang , Shanlong Tang , Shunfen Zhang , Fujiang Hou , Bao Yi , Hongfu Zhang. Dihydroquercetin supplement alleviates colonic inflammation potentially through improved gut microbiota community in mice. Food & Function. Issue 12(22), 2021. P.11420-11434 DOI: 10.1039/d1fo01422f
Jiajie Chen , Xu Sun , Tingting Xia , Qiqi Mao , Liang Zhong .Pretreatment with dihydroquercetin, a dietary flavonoid, protected against concanavalin A-induced immunological hepatic injury in mice and TNF- a / ActD -induced apoptosis in HepG2 cells. Food Function. 2018 Apr 25;9(4):2341-2352. doi : 10.1039/c7fo01073g.
Wang, X., Ouyang, Y.Y., Liu, J., & Zhao, G. (2014). Flavonoid intake and risk of CVD: A systematic review and meta-analysis of prospective cohort studies. British Journal of Nutrition, 111, 1–11.
Liu, XM, Liu, YJ, Huang, Y., Yu, HJ, Yuan, S., Tang, BW,... He, QQ (2017 ). Dietary total flavonoids intake and risk of mortality from all causes and cardiovascular disease in the general population: A systematic review and meta-analysis of cohort studies. Molecular Nutrition & Food Research, 61
Rees, A., Dodd, GF, & Spencer, JPE (2018). The e ff ects of fl avonoids on cardiovascular health: A review of human intervention trials and implications for cerebrovascular function. Nutrients, 10.
Guillermo Gormaz, J., Quintremil, S., & Rodrigo, R. (2015). Cardiovascular disease: A target for the pharmacological effects of quercetin. Current Topics in Medicinal Chemistry, 15, 1735–1742
Xiao, L., Liu, L., Guo, X., Zhang, S., Wang, J., Zhou, F.,... Yao, P. (2017). Quercetin attenuates high fat diet-induced atherosclerosis in apolipoprotein E knockout mice: A critical role of NADPH oxidase. Food and Chemical Toxicology, 105, 22–33
. S Dahmer, E Scott. Health effects of hawthorn - American Family Physician, 2010. 81 (4): 465–468.
Jennifer E. Edwards, Paula N. Brown, Nadia Talent, Timothy A. Dickinson, Paul R. Shipley. A review of the chemistry of the genus Crataegus. Phytochemistry. Volume 79 , July 2012, Pages 5-26. https://doi.org/10.1016/j.phytochem.2012.04.006
I. Orhan . Phytochemical and Pharmacological Activity Profile of Crataegus oxyacantha L. (Hawthorn) - A Cardiotonic Herb. Current Medical Chemistry. 2018;25(37):4854-4865. doi : 10.2174/0929867323666160919095519.
Tunde Jurikova , Jiri Sochor, Otakar Rop, Jiri Mlcek, Stefan Balla, Ladislav Szekeres, Wojtech Adam, Rene Kizek.5 Polyphenolic Profile and Biological Activity of Chinese Hawthorn ( Crataegus pinnatifida BUNGE) Fruits. Molecules 2012, 17(12), 14490-14509; https://doi.org/10.3390/molecules171214490
Feng Shao , Lifei Gu , Huijuan Chen , Ronghua Liu , Huilian Huang , Lanying Chen , Ming Yang Evaluation of Hypolipidemic and Antioxidant Effects in Phenolrich Fraction of Crataegus pinnatifida Fruit in Hyperlipidemia Rats and Identification of Chemical Composition by Ultra-performance Liquid Chromatography Coupled with Quadropole Time-of-flight Mass Spectrometry. Pharmacogn osy Magazine. 2017 Oct-Dec; 13(52): 725–731. doi : 10.4103/pm.pm_402_16
H.BardakciaE.CelepbT.GözetcY.KandH.Kırmızıbekmez.Phytochemical characterization and antioxidant activities of the fruit extracts of several Crataegus taxa. South African Journal of Botany. Volume 124 , August 2019, Pages 5-13
Lillian Barros , Ana Maria Carvalho , Isabel CFR Ferreira . Comparing the composition and bioactivity of Crataegus Monogyna flowers and fruits used in folk medicine. Phytochemical Analysis . Volume 22, Issue 2. P. 181-188. https://doi.org/10.1002/pca.1267
Seyed Fazel Nabawi , Solomon Habtemariam , Touqeer Ahmed , Antoni Sureda , Maria Daglia , Eduardo Sobarzo-Sánchez, Seyed Mohammad Nabawi. Polyphenolic Composition of Crataegus monogyna Jacq.: From Chemistry to Medical Applications. Nutrients 2015, 7(9), 7708-7728; https://doi.org/10.3390/nu7095361
Kamal Ranjbar, Ebrahim Zarrinkalam, Iraj Salehi, Alireza Komaki, Bayan Fayazi. Cardioprotective effect of resistance training and Crataegus oxyacantha extract on ischemia reperfusion-induced oxidative stress in diabetic rats. Pharmacotherapy. Volume 100 , April 2018, Pages 455-460
Subha Rastogi, Madan Mohan Pandey, AKSRawat. Traditional herbs: a remedy for cardiovascular disorders. Phytomedicine . Volume 23, Issue 11 , 15 October 2016, Pages 1082-1089. https://doi.org/10.1016/j.phymed.2015.10.012
A. Urbonaviciute, V. Jacstas, O. Kornisova, V. Janulis, A. Maruska. Capillary electrophoretic analysis of flavonoids in single-styled hawthorn ( Crataegus monogyna Jacq.) ethanolic extracts. Journal of Chromotografy A, 1112(2006). P.339-344
Sychev, A. Ya. Homogenynyy kataliz soedineniyam zhila/ A.Ya. Sychev, V.G. Isak - Chisinau: Shtiintsa, 1988. - 216 p.