DETERMINATION OF THE ACUTE TOXICITY LEVEL OF THE BIOLOGICALLY ACTIVE SUBSTANCE 'ASYETIS'

Surayyokhan Mamatkulova; Nodira G‘ulomova; Ibrahimjon Askarov

Chemistry

No. 6 (2024): FarDU.Ilmiy xabarlar jurnali (Aniq va tabiiy fanlar)

DETERMINATION OF THE ACUTE TOXICITY LEVEL OF THE BIOLOGICALLY ACTIVE SUBSTANCE 'ASYETIS'

Mamatkulova Surayyokhan Abdusamatovna^▸^▾
G‘ulomova Nodira Sherali qizi^▸^▾
Askarov Ibrahimjon Rahmonovich^▸^▾

PDF (Russian)

Submitted: January 21, 2025
Published: 2025-01-24

Abstract

This article presents the assessment of the overall effect and acute toxicity level of a food supplement named "Asyetis," prepared from the aerial parts of medicinal plants such as hyssop and yarrow (bex) growing in the mountainous regions of Uzbekistan, using mice as a model for warm-blooded animals. The sample was tested at the Laboratory of Screening of Biologically Active Substances and Pharmacology at the Bioorganic Chemistry Institute named after A.S. Sodiqov of the Academy of Sciences of the Republic of Uzbekistan.

References

Guide to the conduct of clinical research. Chast pervaya / Pod ed. A.N. Mironova. M.: Grif i K, 2012. - 944 p.
OECD (2001) Guideline for testing of chemicals. Acute Oral Toxicity - Fixed Dose Procedure No. 420 Governing document OESR Test No. 420 "Acute Oral Toxicity - Fixed Dose Procedure".
Abdujabborova, C. (2023). STYPHONOLOBIUM JAPONICUM (SOFORA JAPONICA) THE CHEMICAL COMPOSITION AND APPLICATION IN MEDICINE https://sirpublishers.org/index.php/jomap/article/view/271 https://scholar.google.com/citations?view_op=view_citation&hl=ru&user=hKvs_GgAAAAJ&citation_for_view=hKvs_GgAAAAJ:eQOLeE2rZwMC
Gulomova, N. (2023). КOЛЮЧEЛИCТНИК, ТУPКECТAНCКИЙ МЫЛЬНЫЙ КOPEНЬ: XИМИЧECКИЙ COCТAВ И ПPИМEНEНИE В МEДИЦИНE. Eвpaзийcкий жуpнaл мeдицинcкиx и ecтecтвeнныx нaук, 3(12), 178–183. извлeчeнo oт https://in-academy.uz/index.php/EJMNS/article/view/25175 DOI: https://doi.org/10.5281/zenodo.10437434
Askarov, I. R., & Gulomova, N. S. (2023). Chemical Composition of Sambucus Nigra and its role in folk medicine. International Bulletin of medical sciences and clinical research (Т. 3, Выпуcк 12, cc. 16–20). Zenodo. https://doi.org/10.5281/zenodo.10361541
Jumanova, B. (2023). Chemical Composition of the Marmarak medicinal plant (Salvia officinalis) and use in people’s medicine. В academic research in modern science (Т. 2, Выпуcк 26, cc. 158–162). Zenodo. https://doi.org/10.5281/zenodo.1038941

Most read articles by the same author(s)

Askarov Ibrahimjon Rahmonovich, Mominova Guyokhon Alidjonovna, DETERMINATION OF THE CONTENT OF FLAVONOIDS IN HAWTHORN , Scientific journal of the Fergana State University: No. 3 (2023): FarDU ilmiy xabarlari jurnali (Aniq va tabiiy fanlar)
Ibrahimjon Rakhmonovich Askarov, Abdurakhimova Nodira, Isakov Khayatulla, EXTRACTION OF POLYSACCHARIDES FROM SEEDS AND PEEL OF MELON AND THE DETERMINATION OF THEIR COMPOSITION BY PHYSICO-CHEMICAL METHODS , Scientific journal of the Fergana State University: No. 1 (2023): Scientific journal of the Fergana State University (Exact and natural sciences)

[1] Guide to the conduct of clinical research. Chast pervaya / Pod ed. A.N. Mironova. M.: Grif i K, 2012. - 944 p.

[2] OECD (2001) Guideline for testing of chemicals. Acute Oral Toxicity - Fixed Dose Procedure No. 420 Governing document OESR Test No. 420 "Acute Oral Toxicity - Fixed Dose Procedure".

[3] Abdujabborova, C. (2023). STYPHONOLOBIUM JAPONICUM (SOFORA JAPONICA) THE CHEMICAL COMPOSITION AND APPLICATION IN MEDICINE https://sirpublishers.org/index.php/jomap/article/view/271 https://scholar.google.com/citations?view_op=view_citation&hl=ru&user=hKvs_GgAAAAJ&citation_for_view=hKvs_GgAAAAJ:eQOLeE2rZwMC

[4] Gulomova, N. (2023). КOЛЮЧEЛИCТНИК, ТУPКECТAНCКИЙ МЫЛЬНЫЙ КOPEНЬ: XИМИЧECКИЙ COCТAВ И ПPИМEНEНИE В МEДИЦИНE. Eвpaзийcкий жуpнaл мeдицинcкиx и ecтecтвeнныx нaук, 3(12), 178–183. извлeчeнo oт https://in-academy.uz/index.php/EJMNS/article/view/25175 DOI: https://doi.org/10.5281/zenodo.10437434

[5] Askarov, I. R., & Gulomova, N. S. (2023). Chemical Composition of Sambucus Nigra and its role in folk medicine. International Bulletin of medical sciences and clinical research (Т. 3, Выпуcк 12, cc. 16–20). Zenodo. https://doi.org/10.5281/zenodo.10361541

[6] Jumanova, B. (2023). Chemical Composition of the Marmarak medicinal plant (Salvia officinalis) and use in people’s medicine. В academic research in modern science (Т. 2, Выпуcк 26, cc. 158–162). Zenodo. https://doi.org/10.5281/zenodo.1038941