2-ALMASHGAN 3(H)-XINAZOLIN-4-ON HOSILALARI SINTEZI VA ULARNI NITROLASH REAKSIYALARI

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Ziyadullayev Mirjalol Egamberdi o‘g‘li
Karimov Rixsiboy Kuchkarovich
Adilboyev Samariddin Xolmirza o‘g‘li

Annotatsiya

Ushbu tadqiqot ishida 3(H)-xinazolin-4-onning 2-almashgan hosilalari sintezi hamda reaksiya jarayoni va mahsulot unumiga asosiy ta’sir etuvchi (moddalar nisbati, harorat, vaqt) omillar, sintez qilingan birikmalarning fizik-kimyoviy kattaliklari o‘rganilgan. Sintez qilingan 3(H)-xinazolin-4-onning 2-almashgan hosilalarini nitrolovchi aralashmadan (HNO3+H2SO4) foydalangan holda nitrolash reaksiyalari olib borilgan. Natijada 2-almashgan 3(H)-xinazolin-4-onlarning tarkibidagi benzol xalqasining oltinchi holatida joylashgan harakatchan vodorod atomining -NO2 guruhiga almashib elektrofil birikish reaksiyalari natijasida mos ravishdagi 2-almashgan 3(H)-6-nitroxinazolin-4-onlar sintez qilingan. Sintez qilingan birikmalarni miqdoriy aniqlash spektrofotometrik analiz usuli SF-46 qurilmasida olib borilgan. Erituvchi sifatida 0,1 mol/l HCl eritmasi ishlatilgan. Reaksiya jarayonining borishi va mahsulot hosil bo‘lishi yupqa qatlamli xromatografiya usulida nazorat qilingan. Sintez qilingan birikmalarning tuzilishi IQ, 1H, 13C YaMR spektroskopiya usullarida aniqlangan va tahlil qilingan.

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Bo‘lim
Kimyo
Mualliflar biografiyasi

Ziyadullayev Mirjalol Egamberdi o‘g‘li, Chirchiq davlat pedagogika universiteti

Chirchiq davlat pedagogika universiteti, Fizika va kimyo fakulteti Kimyo kafedrasi dotsenti, kimyo fanlari falsafa bo‘yicha doktori (PhD)

“Alfraganus university” Nodavlat oliy ta’lim tashkiloti, Tibbiyot fakulteti, Kimyo va farmasevtika kafedrasi dotsenti, kimyo fanlari falsafa bo‘yicha doktori (PhD)

Karimov Rixsiboy Kuchkarovich, Toshkent kimyo texnologiya instituti

Toshkent kimyo texnologiya instituti, Yoqilg‘i organik birikmalar kimyoviy texnologiyasi fakulteti, Asosiy organik sintez kafedrasi, texnika fanlari doktori, professor. O‘simlik moddalari kimyosi instituti, Sintetik preparatlar texnologiyasi laboratoriyasi katta ilmiy xodimi, texnika fanlari doktori, professor

Adilboyev Samariddin Xolmirza o‘g‘li, Chirchiq davlat pedagogika universiteti

Chirchiq davlat pedagogika universiteti, Fizika va kimyo fakulteti Kimyo kafedrasi magistranti

Foydalaniladigan adabiyotlar

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