ПРОЦЕСС АЛКИНИЛИРОВАНИЯ НЕКОТОРЫХ ГЕТЕРОАТОМНЫХ АЛЬДЕГИДОВ С АЛКИНАМИ В ПРИСУСТВИИ КАТАЛИТИЧЕСКОЙ СИСТЕМЫ InBr3/Et3N/Et2O
Ключевые слова:
альдегиды, алкины, бромид индия (III), триэтиламин, алкинилирование, ацетиленовые спирты, механизм реакции, выход продукта.Аннотация
Альдегиды, содержащие в своей мoлекуле гетероатом‒ тиофен-2-карбальдегид, 3-метилтиофен-2-карбальдегид, фуран-2-карбальдегид, пиридин-3-карбальдегид, хинолин-2-карбальдегид и 3-бром-4 пиридинкарбальдегидов с ацетилен, фенилацетилен, гексин-1, октином-1 впервые были синтезированы ацетиленовые спирты с использованием каталитической системы InBr3/Et3N/Et2O. Систематически изучалось влияние молярных количественных соотношений исходных веществ, длительности реакции, температуры, природы катализатора и растворителей на выход продукта. Состав, чистота и структура синтезированных ацетиленовых спиртов нового поколения доказаны современными физико-химическими методами.
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