TERPENOIDS AND STEROLS OF PEROVSKIA KUDRJASCHEVII ROOTS
DOI:
https://doi.org/10.56292/SJFSU/vol31_iss5/a122Keywords:
Perovskia kudrjaschevii, triterpenes, sterols, oleanolic acid 3-acetate, ferruginol, stigmasterol, β-sitosterol, oleanolic acid.Abstract
The component composition of Perovskia kudrjaschevii (Lamiacaeae) roots collected during the period of dying off of the aboveground part in the territory of Bostandyk district of Tashkent region was studied. Oleanolic acid 3-acetate, ferruginol, stigmasterol, β-sitosterol, and oleanolic acid were isolated and identified for the first time from the gasoline fraction of the methanol extract of the plant roots. The isolated compounds were identified by studying the data of UV, 1H and 13C NMR spectra, as well as by direct comparison with authentic samples of substances.
References
1. Ковалевская С.С. Род Perovskia. В кн.: Определитель растений Средней Азии. Том IX. -Т.: Фан, Уз ССР, 1987. С.151-155.
2. Mohammadhosseini M., Venditti A., Akbarzadeh A. The genus Perovskia Kar.: ethnobotany, chemotaxon-omy and phytochemistry: a review. Toxin Reviews. Vol. 40 (4), 484 (2021). DOI: 10.1080/15569543.2019.1691013
3. Растительные ресурсы СССР. Цветковые растения, их химический состав, использование. Семей-ства Hippuridaceae-Lobeliacae. Санкт-Петербург: Наука. 1991. C. 63-65.
4. Турдибоев О.А., Тургинов O.T. Таксономический состав рода Salvia L. во флоре Узбекистана. Узб. биол. журнал. №1, 34 (2021).
5. Маматюсупов А.Ш., Ҳамидов Г.Ҳ., Гаппоров Ф.Ш., Махсудова Р.С. Хапри формацияси муҳим асал-шира ва эфир мойи манбаи сифатида. Андижон Давлат Университети. Илмий хабарнома. №4, 27 (2016).
6. O. K. Askarova, Kh. M. Bobakulov, S. A. Sasmakov, T. Kh. Sadullaev, E. Kh. Botirov. Component Composition and Antimicrobial Activity of Perovskia Angustifolia Essential Oil. Russ. J. Bioorg. Chem., 50, 2834 (2024). doi:10.1134/S1068162024070082
7. Юсупова З.А., Бозоров И.Э. Ялпиздошлар (Lamiaceae) оиласи шифoбaxш вa дoривoр турларнинг морфологик ва биoэкoлoгик xoссaлари. Science and Education. Vol. 2. № 4, 55 (2021).
8. Askarova O. K. Perovskia angustifolia, Perovskia botschantzevii va Lophanthus schtschurowskianus o‘simliklarining fenol birikmalari va terpenoidlari. Kimyo fanlari boʻyicha falsafa doktori (PhD) dissertatsiyasi avtoref-erati. Fargʻona, 2024. 45 bet.
9. Жураев М.У., Бобакулов Х.М. , Сиддиков Д.Р. , Аскарова О.К., Ботиров Э.Х., Тургунов К.К., Сасмаков С.А., Ташходжаев Б.. Компоненты корней Perovskia angustifolia. Химия природ. соедин. 2025.№4. С. 668-671.
10. Tanaka N., Niwa K., Kajihara S., Tsuji D., Itoh K., Mamadalieva N.Z., Kashiwada Y. C28 Terpenoids from Lamiaceous Plant Perovskia scrophulariifolia: Their Structures and Anti-neuroinflammatory Activity. Organic Letters. Vol. 22(19), 7667 (23020). DOI:10.1021/acs.orglett.0c02855
11. Tanaka N., Takahashi S., Kajihara S., Tsuji D., Itoh K., Mamadalieva N.Z., Kashiwada Y. Diterpenes from an Uzbek medicinal plant Perovskia scrophulariifolia: Their structures and anti-neuroinflammatory activity. Fitoterapia, Vol. 149. Article 104826 (2021). DOI: 10.1016/j.fitote.2021.104826.
12. Farmani M.M., Danton O., Ramseyer J., Kaiser M., Ebrahimi S.N., Salehi P., Batooli H., Potterat O.,Hamburger M. Antiprotozoal diterpenes from Perovskia abrotanoides. Planta Мed., Vol. 84 (12-13), 913 (2018). DOI:10.1055/a-0608-4946
13. W. Lei, G. Wang, T. Shen, Q. Qiang, Q. Xue, M. Chen, J. Zhang, Y. Luo, Y. M. Hong, C. L. Si, W. Hu. Sec-ondary Metabolites from Stem Barks of Catalpa bungei. Chem Nat Compd., 57, 1111 (2021). DOI:10.1007/s10600-021-03561-1
14. Saeidnia S., Ghamarinia M., Gohari A.R. , Shakeri A.. Terpenes from the root of Salvia hypoleuca Benth DARU. J. Pharm. Sci., 20, 66 (2012). http://www.darujps.com/content/20/1/66
15. Kwon J. H., Chang M. J., Seo H. W., Lee J.H., Min B.S., Na M.K., Kim J.Ch., Woo M.H., Choi J.S., Lee H.K., Bae K.H. Triterpenoids and a sterol from the stem-bark of Styrax japonica and their protein tyrosine phosphatase 1B inhibitory activities. Phytother. Res. 22, 1303 (2008) doi: 10.1002/ptr.2484.
16. Kim M.R., Lee H.H., Hahm K.S., Moon Y.H., Woo E.R. Pentacyclic triterpenoids and their cytotoxicity from the stem bark of Styrax japonica S. et Z. Arch Pharm Res., 27(3), 283 (2004). doi: 10.1007/BF02980060. PMID: 15089031.
17. Jun Dang, Qi-Lan Wang, Yan-Duo Tao, Li-Juan Mei, Xiang Yuan, Jian-Qiang Zhao, Yun Shao, Li Zhang, Terpene from Roots of Salvia prattii, Chem. Nat. Compd, 53, 781 (2017). DOI 10.1007/s10600-017-2120-2
18. Dube N.P., Tembu V.J., Nyemba G. R. Nyemba C. Davison. In vitro cytotoxic effect of stigmasterol deriva-tives against breast cancer cells. BMC Complement Med Ther., 23, 316 (2023). https://doi.org/10.1186/s12906-023-04137-y
19. Ododo M. M., Choudhury M. K., Dekebo A. H. Structure elucidation of β-sitosterol with antibacterial activity from the root bark of Malva parviflora. Springerplus, 29, 5(1) 1210 (2016). DOI 10.1186/s40064-016-2894-x
20. Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antimicrobial Susceptibility Testing. CLSI document M100, 28th Edition. Wayne, PA, USA. 2018.
21. Sasmakov S. A., Gazizov F. Yu., Putieva Zh. M., Wende K., Alresly Z., Lindequist U. Neutral lipids, phos-pholipids, and biological activity of extracts from Zygophyllum oxianum. Chem. Nat. Compd., 48, 11 (2012). DOI:10.1007/s10600-012-0148-x
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Scientific journal of the Fergana State University
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
How to Cite
Most read articles by the same author(s)
- Усманова Наргиза Қудратиллаевна, Ботиров Эркин Хожиакбарович, CHEMICAL COMPONENTS OF SWEET CLOVER- MELILOTUS OFFICINALIS (L.) PALL , Scientific journal of the Fergana State University: No. 5 (2022): Scientific journal of the Fergana State University
- Аскарова Ойдинхон Каримхон кизи, Икромова Гулноза Мубилла кизи, Жураев Мухаммаджон Уктамжон угли, Ботиров Эркин Хожиакбарович, CHEMICAL COMPOSITION OF THE ESSENTIAL OIL FROM THE AERIAL PARTS OF HAPLOPHYLLUM ACUTIFOLIUM , Scientific journal of the Fergana State University: No. 5 (2024): FarDU.Ilmiy xabarlar jurnali (Aniq va tabiiy fanlar)
- , , , , CHEMICAL COMPONENTS OF THE AERIAL PART OF LOPHANTHUS SCHTSCHUROWSKIANUS , Scientific journal of the Fergana State University: No. 6 (2023): FarDU.Ilmiy xabarlar jurnali (Aniq va tabiiy fanlar)