SITRALNING BIOLOGIK FAOLLIGINI VIRTUAL SKRINING USULLARI YORDAMIDA O‘RGANISH
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Annotatsiya
Ushbu maqolada virtual skrining usullaridan foydalangan holda efir moylari tarkibida uchraydigan terepenoidlar sinfiga mansub bo‘lgan sitralning biologik faolligini o‘rganish natijalari yoritilgan. Tadqiqot sitralning potensial biologik ta’sirini bashorat qilish uchun hisoblash usullarini qo‘llaydi, bunda virtual skrining usullari yordamida dorivor moddalarni topish uchun iqtisodiy va vaqtni tejovchi strategiya sifatida foydalaniladi. Fermentlar yoki retseptorlar kabi sitral va maqsadli biomolekulalar o‘rtasidagi o‘zaro ta’sirlarni tahlil qilish orqali ushbu tadqiqot sitralning farmakologik xususiyatlariga asoslangan molekulyar mexanizmlarni ochishga qaratilgan. Olingan natijalar sitralning terapevtik potensialini yaxshiroq tushunishga yordam beradi va turli kasalliklar va sharoitlarga qaratilgan kelajakdagi dori-darmonlarni ishlab chiqish uchun qimmatli tadqiqot ma’lumotlarini beradi.
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