CHEMICAL COMPOSITION AND ANTIOXIDANT ACTIVITY OF MATRICARIA CHAMOMILLA L., JASMINUM OFFICINALE L. AND URTICA DIOICA L.: IMPORTANCE IN FOLK MEDICINE AND PHARMACEUTICALS
DOI:
https://doi.org/10.56292/SJFSU/vol31_iss5/a107Keywords:
antioxidant activity, medicinal plants, neuroprotective effectAbstract
Medicinal plants are valuable sources of bioactive compounds with potential therapeutic applications. This study focuses on the chemical composition and antioxidant potential of three medicinal species: Matricaria chamomilla L., Jasminum officinale L., and Urtica dioica L. The main objective was to identify their key phytochemical constituents and evaluate their antioxidant and neuroprotective properties.
Phytochemical analysis confirmed the presence of flavonoids, phenolic compounds, essential oils, and vitamins (C and K), along with neuroactive phytoestrogens. Chromatographic techniques, including GC–MS and HPLC, were employed to determine the qualitative and quantitative composition of the bioactive compounds. Antioxidant activity was assessed using DPPH, FRAP, and adrenaline autoxidation assays.
The results indicated a high concentration of antioxidant compounds in all three species. M. chamomilla and J. officinale demonstrated pronounced neuroprotective and anxiolytic effects, whereas U. dioica exhibited significant benefits for cerebral circulation and oxidative balance.
In conclusion, the findings confirm the strong antioxidant and neuroprotective potential of these medicinal plants and support their further investigation as promising natural agents for preventing or managing nervous system disorders.
References
1. Singh O. et al. Chamomile (Matricaria chamomilla L.): an overview //Pharmacognosy reviews. – 2011. – T. 5. – №. 9. – S. 82.
2. El Mihyaoui A. et al. Chamomile (Matricaria chamomilla L.): a review of ethnomedicinal use, phytochem-istry and pharmacological uses //Life. – 2022. – T. 12. – №. 4. – S. 479.
3. Akram W. et al. An updated comprehensive review of the therapeutic properties of Chamomile (Matricaria chamomilla L.) //International Journal of Food Properties. – 2024. – T. 27. – №. 1. – S. 133-164.
4. Chauhan R. et al. A comprehensive review on biology, genetic improvement, agro and process technolo-gy of German chamomile (Matricaria chamomilla L.) //Plants. – 2021. – T. 11. – №. 1. – S. 29.
5. Al-Khazraji S. M. Evaluation of antibacterial activity of Jasminum officinale //IOSR Journal of Pharmacy and Biological Sciences. – 2015. – T. 10. – №. 1. – S. 121-124.
6. Sahu R. et al. Pharmacological and therapeutic properties of jasminum officinale. L: a review //Indian Journal of Ecology. – 2022. – T. 49. – №. 3. – S. 1122-1128.
7. Hussain M. et al. Comparative In vitro study of antimicrobial activities of flower and whole plant of Jas-minum officinale against some human pathogenic microbes //Journal of Pharmacy and Alternative Medicine. – 2013. – T. 2. – №. 4. – S. 33-43.
8. Thakur M. et al. Hypoglycemic and antioxidant activities of Jasminum officinale L. with identification and characterization of phytocompounds //Heliyon. – 2024. – T. 10. – №. 21.
9. Joshi B. C., Mukhija M., Kalia A. N. Pharmacognostical review of Urtica dioica L //International Journal of Green Pharmacy (IJGP). – 2014. – T. 8. – №. 4.
10. Dar S. A. et al. Pharmacological and toxicological evaluation of Urtica dioica //Pharmaceutical Biology. – 2013. – T. 51. – №. 2. – S. 170-180.
11. Halder S., Sharma A. A review on Urtica dioica L //World J Pharm Sci. – 2017. – T. 6. – S. 404-421.
12. Olsen C. The ecology of Urtica dioica //Journal of Ecology. – 1921. – T. 9. – №. 1. – S. 1-18.
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Scientific journal of the Fergana State University

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.