M-TOLIL XLORASETAT ASOSIDA M-TOLIL-4-METILFENOKSIASETAT SINTEZ USULI

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Nashr qilingan: fev 3, 2025
Kalit so‘zlar:
m-krezol, 4-metilfenol, biologik faollik, antibakterial, analgetik mikroorganizm, bakteritsid, xloratsetillash, katalizatorlar, mexanizm, ekstraktsiya, erituvchi, dielektrik konstantalari, sintez.

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Mamatkulov Nematillo Narzullayevich
O‘zbekiston Milliy universiteti
https://orcid.org/0009-0000-2728-4507
Dilfuza Muxammadjonovna Xatamova
Farg‘ona davlat universiteti
https://orcid.org/0009-0001-5912-1320

Annotatsiya

Ushbu tadqiqot ishida m-krezolni turli xil sharoitlarda xlorasetilxloid bilan reaksiyalari olib borildi. m-Krezolni katalitik miqdordagi FeCl3, FeCl3×6Н2О, ZnCl2, Fe2(SO4)3 va TAA lar ishtirokida xlorasetilxlorid bilan reaksiyasi olib borilgangada, izomerlar aralashmasi hosil bo‘lishi aniqlandi. Individual modda sintez qilish maqsadida tadqiqotlar davom etirilganda, benzol eritmasida m-tolilxlorasetat sintez qilish uslubi topildi. Ushbu reaksiyaning reaksiya mexanizmi ishlab chiqildi va nazariy jihatdan asoslab berildi. m-Tolilxlorasetatni 4-metilfenol bilan nuklefil almashinish reaksiyasiya benzol, aseton, dioksan, DMF, DMSO eritmalarida olib borildi. Reaksiya unumi DMSO eritmasida yuqori bo‘lib, m-tolil-4-metilfenoksiasetat unumi 95% ni tashkil etdi.

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Qanday qilib iqtibos keltirish kerak
Mamatkulov Nematillo Narzullayevich, & Dilfuza Muxammadjonovna Xatamova. (2025). M-TOLIL XLORASETAT ASOSIDA M-TOLIL-4-METILFENOKSIASETAT SINTEZ USULI . Farg’ona Davlat Universiteti, 30(6), 178. Retrieved from https://journal.fdu.uz/index.php/sjfsu/article/view/6088
Maqola
№. 6 (2024): FarDU ilmiy xabarlari jurnali ILOVA TO'PLAM (Aniq va tabiiy fanlar)
Bo‘lim
Kimyo
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Mualliflar biografiyasi

Mamatkulov Nematillo Narzullayevich, O‘zbekiston Milliy universiteti

O‘zbekiston Milliy universiteti, kimyo fanlar nomzodi, dotsent

Dilfuza Muxammadjonovna Xatamova, Farg‘ona davlat universiteti

Farg’ona davlat universiteti kimyo kafedrasi katta o’qituvchisi

Foydalaniladigan adabiyotlar

Nagaraj A., Nagarathinam N., Manju J., Kumari К. and Amarajothi D. Acetylation of alcohols, amines, phenols, thiols under catalyst and solvent-free conditions // Chemistry (An Open Access Journal from MDPI), 2019. -P. 70

Tong-Hyok Cha, Gum-Chol Kim, Kwang-Jin Ri. Molecular properties calculated with Gaussian basis sets optimized in molecule’s local environments // Chemical Physics. Volume 570, 1 June 2023, 111890

Abdushukurov А.К., Mamatkulov N.N., Ahmedov К.Н., Bobonazarob A., Muratov A. The synthesis of biologically active compounds using phenylchloracetate//International workshop on biotechnology commercialization and security. Scientific materials. Tashkent-2003. -P. 14-17.

Mamatkulov N.N., Ochilov M., Pattaeva Z. Synthesis of Organic Fertilizers Based on Phenol and Benzoic Acid Derivatives and Application Technology to Plants// Journal of Innovative Studies of Engineering Science ( JISES ) Volume: 02 Issue: 04 | 2023 Germaniya. Pp.94-97.

Мазитова А.К., Нафикова Р.Ф., Аминова Г.К. Пластификаторы поливинилхлорида// Наука и эпоха: монография. Воронеж-2011. -С 276-296.

Pattaeva Z. S., Mamatkulov N. N. Testing the biological activity of some properties of phenylchloracetate in the pass online program// International Journal of Economy and Innovation.Vol. 37.GospodarkaiInnowacje. Poland. 2023. Pp. 74-78.

Садикова С.Б., Абдушукуров А.К., Чориев А.У. Хлорацеттилирование гидрохинона и его эфиров кислотами Льюиса//Universium химия и биология. -2019. -№. 5(59). -С. 52-55.