ХИМИЧЕСКИЕ СВОЙСТВА АМИГДАЛИНА И ЕГО ВЛИЯНИЕ НА ЗДОРОВЬЕ ЧЕЛОВЕКА
Боковая панель статьи
Основное содержимое статьи
Аннотация
В статье представлена информация об амигдалине и его химических свойствах, который относится к классу природных цианогликозидов. В статье также упоминается важность амигдалина в лечении различных заболеваний, таких как астма, бронхит, эмфизема легких, фиброз легких, заболевания желудочно-кишечного тракта, онкологические заболевания, заболевания почек и других.
Информация о статье
Библиографические ссылки
Araya E, Rodriguez A, Rubio J et al. Synthesisand evaluation of diverse analogs of amygdalin as potential peptidomimetics of peptide T. Bioorg. Med. Chem. Lett. 15,1493–1496 (2005).
ChristopheBliard∗GeorgesMassiotSergeNazabadioko Amygdalin as building block in oligosaccharide synthesis Tetrahedron Letters Volume 34, Issue 32, 6 August 1993, Pages 5083-5084 https://doi.org/10.1016/S0040-4039(00)60681-0
Amit Lather, Sunil Sharma , Anurag Khatkar. Amygdalin based G 6 P synthase inhibitors as novel preservatives for food and harmaceutical products. Scientific RepoRtS | (2020) 10:1390-1393. https://doi.org/10.1038/s41598-020-70895-1
Islamiyat Folashade Bolarinwa. Synthesis and Characterization of Hapten-Protein Conjugates for Antibody Production against Cyanogenic Glycosides. Journal of Food Protection, Vol. 78, No. 7, 2015, Pages 1408–1413. doi:10.4315/0362-028X.JFP-15-033
Rabia Sohail, Shah Rukh Abbas. Evaluation of amygdalin-loaded alginate-chitosan nanoparticles as biocompatible drug delivery carriers for anticancerous efficacy. International Journal of Biological Macromolecules 153 (2020) 36–45.
Chan TY. A probable case of amygdalin-induced peripheral neuropathy in a vegetarian with vitamin B12 deficiency. Ther Drug Monit 2006;28:140.
Chang HK, Yang HY, Lee TH, Shin MC, Lee MH, Shin MS, et al.Armeniacae semen extract suppresses lipopolysaccharide-induced
expressions of cyclooxygenase [correction of cycloosygenase]-2 and
inducible nitric oxide synthase in mouse BV2 microglial cells. Biol
Pharm Bull 2005;28:449-454.
Chang HK, Shin MS, Yang HY, Lee JW, Kim YS, Lee MH, et al. Amygdalin induces apoptosis through regulation of Bax and Bcl-2 expressions
in human DU145 and LNCaP prostate cancer cells. Biol Pharm Bull
;29:1597-602.
Park HJ, Yoon SH, Han LS, Zheng LT, Jung KH, Uhm YK, et al. Amygdalin inhibits genes related to cell cycle in SNU-C4 human colon cancer
cells. World J Gastroenterol 2005;11:5156-5161.
Guo J, Wu W, Sheng M, Yang S, Tan J. Amygdalin inhibits renal fibrosis in chronic kidney disease. Mol Med Rep 2013;7:1453-1457.
Baroni A, Paoletti I, Greco R, Satriano RA, Ruocco E, Tufano MA,
et al. Immunomodulatory effects of a set of amygdalin analogues
on human keratinocyte cells. Exp Dermatol 2005;14:854-859.
Mirmiranpour H, Khaghani S, Zandieh A, Khalilzadeh OO,Gerayesh-Nejad S, Morteza A, et al. Amygdalin inhibits angiogenesisin the cultured endothelial cells of diabetic rats. Indian J PatholMicrobiol 2012;55:211-214.
Liu C, Li X, Yang H, Mao X, Wang J, Gao W. Effect of Natural beta-Glucosidase Inhibitors in Reducing Toxicity of Amygdalin in Persicae Semen. Phytother Res. 2017; 31(5): 771–777. doi: 10.1002/ptr.5798.