DETERMINATION OF FLAVONOIDS IN THE FRUIT PERICARP OF HORSE CHEST-NUT (AESCULUS HIPPOCASTANUM L.)

Ibrohimjon Rakhmonovich Asqarov; Gulruhsor Sanjarbek qizi Kimsanova

doi:10.56292/SJFSU/vol31_iss5/a112

Authors

Ibrohimjon Rakhmonovich Asqarov

Andijan State University

https://orcid.org/0000-0003-1625-0330
Gulruhsor Sanjarbek qizi Kimsanova

Andijan State University

https://orcid.org/0009-0005-5354-7012

DOI:

https://doi.org/10.56292/SJFSU/vol31_iss5/a112

Keywords:

Horse chestnut, varicose veins, flavonoids, gallic acid, quercetin, rutin.

Abstract

In recent decades, medicinal plants have garnered significant scientific attention as natural alternatives to synthetic pharmaceuticals due to their low toxicity, high efficacy, and minimal side effects. Among these, horse chestnut (Aesculus hippocastanum L.) is one of the most widely used medicinal plants in both traditional medicine and modern pharmaceutical formulations. Horse chestnut is well known for its content of biologically active compounds, including esculin, escin, aescin, and a diverse range of flavonoids. These compounds have demonstrated considerable potential in the treatment of vascular diseases. Flavonoids, in particular, are recognized for their potent venotonic, anti-inflammatory, and antioxidant activities. Their use is widespread in the treatment of chronic venous insufficiency, varicose veins, hemorrhoids, and thrombophlebitis. Numerous studies have confirmed that horse chestnut extracts can enhance blood circulation, strengthen capillary walls, and effectively reduce swelling and inflammation.

Author Biographies

Ibrohimjon Rakhmonovich Asqarov, Andijan State University

Professor, Department of Chemistry, Andijan State University; Doctor of Chemical Sciences; Honored Inventor of Uzbekistan; Chairman of the Academy of Traditional Medicine of Uzbekistan
Gulruhsor Sanjarbek qizi Kimsanova, Andijan State University

PhD Candidate, Andijan State University

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