SYNTHESIS OF ACETYLENE ALCOHOLS BASED ON ENANTIOSELECTIVE ETHYNYLATION OF KETONES WHICH HAVE VARIOUS NATURE

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Published: Nov 16, 2023
Keywords:
calcium carbide, ketones, tetra-n-butylammonium fluoride, acetylene alcohols, major and minor products, reaction mechanism, product yield.

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Sarvinoz Tirkasheva
Chirchik State Pedagogical University
Odiljon Ziyadullayev
Chirchik State Pedagogical University
Valentin Nenaydenko
Moscow State University
Qo‘shboqov Farrux Zokir o‘g‘li Qo‘shboqov Farrux Zokir o‘g‘li
Chirchik State Pedagogical University

Abstract

For the first time, terminal acetylene alcohols were synthesized by the enantioselective ethynylation reaction of some ketones using calcium carbide in the TBAF·3H2O/DMSO/H2O catalytic system. The influence of the nature and amounts of solvents, catalysts, reagents and substrates on product yield was studied. The most alternative conditions of control and direction of reactions are determined. The series of product formation efficiency of selected ketones was developed. Synthesized terminal acetylene alcohols were identified, their composition, purity, structure and specific constants were proved by modern physico-chemical methods.

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How to Cite
Tirkasheva , S., Ziyadullayev , O., Nenaydenko , V., & Qo‘shboqov Farrux Zokir o‘g‘li, Q. F. Z. o‘g‘li. (2023). SYNTHESIS OF ACETYLENE ALCOHOLS BASED ON ENANTIOSELECTIVE ETHYNYLATION OF KETONES WHICH HAVE VARIOUS NATURE. Scientific Journal of the Fergana State University, 29(3), 138. Retrieved from https://journal.fdu.uz/index.php/sjfsu/article/view/2604
Issue
No. 3 (2023): FarDU ilmiy xabarlari jurnali (Aniq va tabiiy fanlar)
Section
Chemistry
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Author Biographies

Sarvinoz Tirkasheva , Chirchik State Pedagogical University

Chirchiq davlat pedagogika universiteti, Fizika va kimyo fakulteti, kimyo kafedrasi tayanch doktoranti

Odiljon Ziyadullayev , Chirchik State Pedagogical University

Chirchiq davlat pedagogika universiteti, ilmiy ishlar va innovatsiyalar bo‘yicha prorektori, kimyo fanlari doktori, professor

Valentin Nenaydenko , Moscow State University

Moskva davlat universiteti, Kimyo fakulteti, organik kimyo kafedrasi mudiri, kimyo fanlari doktori, professor

Qo‘shboqov Farrux Zokir o‘g‘li Qo‘shboqov Farrux Zokir o‘g‘li, Chirchik State Pedagogical University

Chirchiq davlat pedagogika universiteti, Fizika va kimyo fakulteti, kimyo kafedrasi tayanch doktoranti

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